Vermillion
Vermillion offers an authentic wet-on-wet painting experience. Pick up your palette, choose your brush, and start painting without the mess. A unique feature of Vermillion is the ability to open a web browser in-game, so you can have an instructional YouTube video next to your easel.
You can also have it projected onto your easel, so you can trace whatever picture you want to paint. If you would like to stream while painting, there is a spectator camera that gives your viewers the ability to watch you complete your masterpiece.